Charlie Sheen and Steve Carell will battle it out at the 60th Annual Primetime Emmy Awards in September.
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The Two and a Half Men actor and The Office star will compete for the Lead Actor in a Comedy accolade at the ceremony in Los Angeles.
Joining Steve and Charlie in the category are Monk actor Tony Shalhoub, Lee Pace from Pushing Daisies and 30 Rock star Alec Baldwin.
In the female equivalent, Christina Applegate and America Ferrera are the frontrunners for their roles in Samantha Who? and Ugly Betty, respectively. They will compete against Julia Louis-Dreyfus from The New Adventures of Old Christine, Tina Fey of 30 Rock fame and Weeds star Mary Louise-Parker at the event to be held at the Nokia Theatre.
Other notable competitors include Glenn Close and Sally Field in the Lead Actress in a Drama category and Hugh Laurie and James Spader who are up for the Lead Actor in a Drama award.
This is the first year US reality TV hosts will be recognised.
Project Runway host Heidi Klum will battle it out with American Idol presenter Ryan Seacrest, among others.
US TV mini-series John Adams earned the most nominations with an incredible 23 nods from the voting board, while 30 Rock led the comedy categories with 17 nominations.
The Emmy Awards have already caused controversy, with Grey’s Anatomy star Katherine Heigl removing herself from contention after blaming the medical drama’s writers for not giving her good enough material.
Following Katherine’s decision, Lindsay Lohan also withdrew from the competition, saying her guest role in Ugly Betty was not important enough to warrant a nomination.
The 60th annual Primetime Emmy Awards, full list of nominees:
Lead Actor in a Comedy: Tony Shalhoub, Monk
Steve Carell, The Office
Lee Pace, Pushing Daisies
Alec Baldwin, 30 Rock
Charlie Sheen, Two and a Half Men
Lead Actor in a Drama:
James Spader, Boston Legal
Bryan Cranston, Breaking Bad
Michael C. Hall, Dexter
Hugh Laurie, House
Gabriel Byrne, In Treatment’
Jon Hamm, Mad Men
Lead Actress in a Comedy:
Julia Louis-Dreyfus, The New Adventures of Old Christine
Christina Applegate, Samantha Who?
Tina Fey, 30 Rock
America Ferrera, Ugly Betty
Mary-Louise Parker, Weeds
Lead Actress in a Drama:
Sally Field, Brothers and Sisters
Kyra Sedgwick, The Closer
Glenn Close, Damages
Mariska Hargitay, Law and Order: Special Victims Unit
Holly Hunter, Saving Grace
Supporting Actor in a Comedy:
Jeremy Piven, Entourage
Kevin Dillon, Entourage
Neil Patrick Harris, How I Met Your Mother
Rainn Wilson, The Office
Jon Cryer, Two And A Half Men
Supporting Actor in a Drama:
William Shatner, Boston Legal
Ted Danson, Damages
Zeljko Ivanek, Damages
Michael Emerson, Lost
John Slattery, Mad Men
Supporting Actress in a Comedy:
Kristin Chenoweth, Pushing Daisies
Jean Smart, Samantha Who?
Amy Poehler, Saturday Night Live
Holland Taylor, Two and a Half Men
Vanessa Williams, Ugly Betty
Supporting Actress in a Drama:
Candice Bergen, Boston Legal
Rachel Griffiths, Brothers and Sisters
Chandra Wilson, Grey’s Anatomy
Sandra Oh, Grey’s Anatom
Dianne Wiest, In Treatment
Host For a Reality or Reality-Competition:
Ryan Seacrest, American Idol
Tom Bergeron, Dancing with the Stars
Howie Mandel, Deal or No Deal
Heidi Klum, Project Runway
Jeff Probst, Survivor
Outstanding Comedy Series:
Curb Your Enthusiasm
Entourage
The Office
30 Rock
Two and a Half Men
Outstanding Drama Series:
Boston Legal
Damages
Dexter
House
Lost
Mad Men
